Cholestatic Pruritus Epidemiology Forecast to 2030 by DelveInsight

 

Cholestatic Pruritus Epidemiology” report has been added to DelveInsight

Cholestatic Pruritus Overview

Cholestasis is defined as a decrease in bile flow due to the impaired secretion by hepatocytes or due to the obstruction of bile flow through intra-or extra-hepatic bile ducts. This impairment in bile secretion occurs at somewhere between the liver cells (which produce bile) and the duodenum (the first segment of the small intestine).

Cholestatic Pruritus Epidemiology Forecast

DelveInsight’s ‘Cholestatic Pruritus – Epidemiology Forecast to 2030’ report delivers an in-depth understanding of the disease, historical and forecasted Cholestatic Pruritus epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.

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Regions Covered

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan

Cholestatic Pruritus Epidemiology Insights

Historically, pruritus has been observed to accompany jaundice, but it is not uncommon to see pruritus as the first manifestation of cholestasis even before the onset of jaundice or other symptoms. There is considerable variation in the frequency and prevalence of pruritus in different Cholestatic conditions.

Key facts of Cholestatic Pruritus report

  • As per the Royal College of Obstetricians and Gynaecologists, United Kingdom, obstetric cholestasis is a multifactorial condition of pregnancy characterized by pruritus in the absence of a skin rash with abnormal liver function tests. In England, this condition affects nearly 1% of pregnancies in multiethnic populations.
  • Patients with genetic biliary disorders such as BRIC or PFIC commonly suffer from cholestatic itch. Chronic pruritus is characteristic for the immune-mediated cholestatic disorders PBC, PSC, and SSC, with a lifetime prevalence of up to 70–80%. These numbers were substantiated by a national cohort study from the UK, in which 73.5% of the patients experienced pruritus at some point during their disease, 34.5% reported on persistent pruritus, and 11.7% on severe pruritus. Data from Germany indicated a point prevalence of chronic pruritus of 56% of out of which almost 70% reported on persistent itch for many years.
  • There is considerable variation in the frequency and prevalence of pruritus in different cholestatic conditions. For instance, it is experienced by up to 80% of patients with primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) and by 5–15% of patients with chronic hepatitis C at any time during the course of their disease. It is less common in patients with extrahepatic cholestatic pruritus, as in one series pruritus occurred in 17% of all patients with non-neoplastic obstructive jaundice and in 45% of patients with neoplastic obstructive jaundice.

Cholestatic Pruritus Epidemiology Perspective

The Cholestatic Pruritus epidemiology division provides insights about historical and current patient pool and forecasted trend for every seven major countries. The Cholestatic Pruritus epidemiology data are studied through all possible division to give a better understanding of the Disease scenario in 7MM. The Cholestatic Pruritus epidemiology segment covers the epidemiology data in the US, EU5 countries (Germany, Spain, Italy, France, and the UK), and Japan from 2017 to 2030. It also helps to recognize the causes of current and forecasted trends by exploring numerous studies, survey reports and views of key opinion leaders.

Cholestatic Pruritus Epidemiology Segmentation

  • Total Prevalent Population
  • Prevalent Cases
  • Gender-specific Prevalent Population
  • Severity-specific Prevalent Population
  • Diagnosed and Treatable Population

Cholestatic Pruritus Epidemiology Report Highlights

  • 11-Year Forecast of Cholestatic Pruritus epidemiology
  • 7MM Coverage
  • Total Cases of Cholestatic Pruritus
  • Total Cases of Cholestatic Pruritus according to segmentation
  • Diagnosed cases of Cholestatic Pruritus

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Table of content

  1. Key Insights
  2. Executive Summary of Cholestatic Pruritus
  3. Cholestatic Pruritus: Disease Background and Overview
  4. Patient Journey
  5. Epidemiology and Patient Population
  6. Treatment Algorithm, Current Treatment, and Medical Practices
  7. KOL Views
  8. Unmet Needs
  9. Appendix
  10. DelveInsight Capabilities
  11. Disclaimer
  12. About DelveInsight

Cholestatic Pruritus Epidemiology Key Assessments

  • Patient Segmentation
  • Disease Risk and Burden
  • Risk of disease by the segmentation
  • Factors driving growth in a specific patient population

Why should you buy this report?

  • Develop business strategies by understanding the trends shaping and driving the global Cholestatic Pruritus market
  • Quantify patient populations in the global Cholestatic Pruritus market to improve product design, pricing, and launch plans
  • Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for Cholestatic Pruritus therapeutics in each of the markets covered
  • Understand the magnitude of Cholestatic Pruritus population by its epidemiology
  • The Cholestatic Pruritus Epidemiology Model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based with transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over 11-year forecast period using reputable sources

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